Study: Anti-Aging Supplements Best Taken In The Middle Ages
To get the most out of so-called anti-aging supplements, 's best to take them during middle age, rather than waiting until after age 65, a new study in rats suggests.
Middle-aged rats showed improvement in their physicalabilities after taking anti-aging supplements, while the older rats did not, researchers say.
"It is possible that there is a window during whichthese associations will work, if the intervention is given after t work itwon time," said the scientist study Jinze Xu, a postdoctoral researcher atthe University of Florida 's Institute on Ageing .
However, results from studies in rats do not apply necessarily tohumans, and further research will be needed to confirm these findings.
Rodent power
Scientists to fully understand all procedures thatlead a loss of age aspeople function. But an increasing number of research on the cells' power plants, called mitochondria, as importantplayer during aging. Mitochondria are largely responsible for creating energywithin a cell, but also produce the so-called free radicals, which are moleculeswith extra electrons that can damage – throughout the cell and within themitochondria same. Too much damage can cause mitochondria to stop workingproperly.
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To address this problem, many anti-aging studies andsupplements geared towards reducing the effects of free radicals.
The current study examined a commercially available supplementmarketed to relieve chronic fatigue and protect against aging muscles. Thesupplement containing the antioxidant coenzyme Q10, creatine – a composite thataids muscle performance – and ginseng, which has also been shown to haveantioxidant properties. (Antioxidants improve damage caused by free radicals.)
The researchers fed the supplement medium aged21-month-old and late-middle aged 29-month-old mice – equivalent to 50 – to65 years and 65 – to 80 year old man, respectively – for six weeks, andmeasured how strong legs could have a grip. Grip strength in rats is analogousto physical performance in humans, and the deterioration of grip strength canprovide useful information about muscle weakness or loss observed in older adults.
At the end of six weeks, grip strength had improved 12percent in middle-aged rats compared with controls. It wasfound improve the older group.
Measurement of mitochondrial function correspondedwith findings grip strength. Stress tests show that mitochondrialfunction improved 66 percent compared with the control group in middle-aged rats, but not before. To show these anti-aging supplements can have more power before the great age andother functional reductions set in, the researchers said.
More power to thepowerhouses
Interestingly, while the older mice had no inphysical improve efficiency and functioning of the mitochondria were less free radicaldamage compared with control mice.
The researchers speculate that while helpedto complete reduction of free radical damage, the damage may be too high in animal theseold the phenomenon to restore the reality of mitochondrial function.
Future research should focus on boosting health themitochondria, the researchers say, because well-working producefewer mitochondria to free radicals. Also, clinical trials need to be performed to test the effectivenessof supplements in humans.
The results were published last week in the journal PLoSOne. Supplement manufacturers donated the amount used for studyand provided support for the postdoctoral researcher and analysis. Animalsused The study was paid for through grants from the National Institute onAging.
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